Aliens may be virtually impossible to control, but what if man could anticipate their actions? In a deep space research station, Dr. Paul Church studies Alien behavioral responses. How does an Alien track its prey? Can an Alien distinguish whether a human is armed? Will an Alien ever retreat from an attack? Test after test, patterns of behavior are revealed to Church... patterns which are predictable.

The station is carefully supervised; every precaution is taken, but everyone knows the risks. When an apparent saboteur is killed by an escaped Alien, the site of scientific research gives way to a homicide investigation. Col. Dr. Anthony Crespi, the stalwart survivor of Aliens: Backsplash (featured in Dark Horse Comics #12 and 13), suspects that the Alien subject may not have escaped on its own, and is determined to uncover the truth.