A heroic pack of canines known as the Wise Dogs set off on a mission to clean up a Pennsylvania corridor plagued by seemingly unrelated occult disturbances that include a fire salamander and a horde of mutant lurkers. A link is found among the various disturbances, leading our heroes to a mountain village inhabited by a survivalist witch-cult who have discovered the existence of a ''Blood Lure'' attracting occult forces, creatures, and many more terrors to Burden Hill! 

* The eight-time Eisner-winning series is back!

* Variant Cover by Rafael Albuquerque!

''Beasts of Burden balances humor, heart, and horror and fosters the contrast necessary to elevate a genre.''--MTV